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The Single-use Bioreactors Market is projected to reach $10.3 billion by 2030, at a CAGR of 15.8% from 2023 to 2030.

Single-use bioreactors enable manufacturers to use disposable technologies like single-use bags in upstream manufacturing processes, traditionally dominated by stainless steel equipment. These bioreactors are favored over stainless steel counterparts because sterilizing traditional bioreactors via autoclaving is a time-consuming, costly, and often inconsistent process in pharmaceutical manufacturing. In contrast, single-use bioreactors utilize pre-sterilized disposable bags, significantly reducing the time and costs associated with sterilization. With fewer mechanical components than traditional systems, single-use bioreactors are also more cost-effective to maintain, making them a preferred choice for biopharmaceutical companies.

The market’s growth is primarily driven by the expanding biopharmaceutical sector, increasing adoption of disposable technologies in the pharmaceutical and biotechnology industries, capacity expansions at biopharmaceutical manufacturing plants, rising pharmaceutical R&D investments, the growing popularity of biosimilars, and the increasing prevalence of chronic diseases. Additionally, emerging economies, along with the growing use of personalized medicine and cell and gene therapies, present significant opportunities for market players.

Top 10 Companies Operating in the Single-use Bioreactors Market:

Thermo Fisher Scientific Inc. (U.S.)
Established in 1956 and headquartered in Massachusetts, U.S., Thermo Fisher serves various sectors, including pharmaceuticals, biotechnology, and healthcare. The company operates through four divisions: Life Sciences Solutions, Analytical Instruments, Specialty Diagnostics, and Laboratory Products & Biopharma Services. Its single-use bioreactors are offered through the Life Sciences Solutions segment. Thermo Fisher has a strong global presence, with offices and production facilities in numerous countries such as the U.S., Mexico, Brazil, Germany, India, and China.

Danaher Corporation (U.S.)
Founded in 1984 and based in Washington D.C., Danaher Corporation designs, manufactures, and markets products for medical, industrial, and commercial sectors. The company operates through four business segments: Biotechnology, Life Sciences, Diagnostics, and Environmental & Applied Solutions. Danaher provides single-use bioreactors through its subsidiary Cytiva under the Biotechnology segment. With a presence in more than 60 countries, including the U.S., China, and Germany, Danaher distributes its products via direct sales personnel and independent distributors.

Merck KGaA (Germany)
Established in 1668 and headquartered in Darmstadt, Germany, Merck is a global healthcare and technology company. It operates through three main segments: Life Science, Healthcare, and Electronics. Within the Life Science segment, the Process Solutions sub-segment offers single-use bioreactors to academic institutions, pharmaceutical companies, and biotech organizations. Merck has a global footprint, serving customers in a wide array of industries.

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Eppendorf AG (Germany)
Founded in 1945 and based in Hamburg, Germany, Eppendorf AG develops and commercializes biotechnology products and services for laboratories. The company operates across four segments: Liquid Handling, Consumables, Separation & Instrumentation, and Lab Solutions, with single-use bioreactors offered under Lab Solutions. Eppendorf operates in over 30 countries, including major markets such as the U.S., China, and India.

Sartorius AG (Germany)
Sartorius, founded in 1870 and headquartered in Gottingen, Germany, is a supplier of laboratory equipment and biopharmaceutical solutions. The company operates through two segments: Bioprocess Solutions and Lab Products & Services. Sartorius’ Bioprocess Solutions Division provides biopharmaceutical processing equipment, including single-use bioreactors. The company has production facilities in Germany, France, and Puerto Rico, and a global presence in over 20 countries.

Solaris Biotechnology Srl (Italy)
Established in 2002 and headquartered in Mantovano, Italy, Solaris Biotechnology manufactures equipment for the biotech, pharmaceutical, food & beverage, and dairy industries. It offers bioreactors, fermenters, and filtration systems. Solaris operates in the U.S. through its subsidiary and in Malaysia through a sales and service facility. The company has over 30 distributors worldwide.

Cellexus International Ltd. (U.K.)
Founded in 2017 and based in Scotland, U.K., Cellexus International Ltd. develops and manufactures single-use airlift bioreactor systems under the CellMaker brand. These systems are used for cell culture and fermentation, helping life sciences and pharmaceutical customers. The company holds ISO 9001:2015 certification for its quality management system.

Distek, Inc. (U.S.)
Founded in 1976 and headquartered in New Jersey, U.S., Distek, Inc. specializes in laboratory testing instruments for the pharmaceutical and biotechnology industries. Distek’s portfolio includes the BIOne single-use bioreactor for cell culture and the BIOne 1250 bioreactor control system. The company serves a diverse customer base, including pharmaceutical manufacturers and research institutions, with a distribution network spanning North America, Asia, and the Middle East.

CESCO Bioengineering Co., Ltd. (Taiwan)
Established in 2002 and headquartered in Taichung, Taiwan, CESCO Bioengineering provides cell culture products and bioprocess equipment. The company offers single-use bioreactors under the BelloCell and TideCell brands, catering to biopharmaceutical researchers and manufacturers worldwide.

PBS Biotech, Inc. (U.S.)
Founded in 2006 and based in California, U.S., PBS Biotech develops single-use manufacturing solutions for the cell therapy industry. The company’s Vertical-Wheel bioreactor systems are designed for small-scale process development and large-scale clinical production, facilitating the development of regenerative medicines.

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