The High-performance Liquid Chromatography (HPLC) Market will register a CAGR of 5.2% during the forecast period to reach $7.9 billion by 2030, says Meticulous Research®. HPLC has been used as a vital separation tool across all branches of science. It is often the only means of separating components from complex mixtures. The technique is based on operating pressure ranging from 5,800 PSI to 7,000 PSI (400 bar-500 bar), whereas the operating pressure for ultra-high-performance liquid chromatography (UPLC) is between 7,000 PSI to 20,000 PSI. There are various HPLC separation modes, including normal phase, reverse phase, and ion exchange, of which reverse phase HPLC is a widely adopted technique. Since the outbreak of the COVID-19 pandemic, research related to COVID-19 using HPLC to understand the SARS-CoV-2 virus and develop better therapies, vaccines, and diagnostic tools has increased, leading to the adoption of HPLC products. The HPLC technique has also been used for various other applications, including food quality testing and environmental sample testing for environment monitoring.
Rising R&D investments in the pharmaceutical & biotechnology industries, technological advancements in HPLC, rising food safety concerns, and growth in policies and initiatives to reduce environmental pollution. Moreover, emerging economies and bio-clusters’ development to foster research is expected to create growth opportunities for the market.
Here are the top 10 companies operating in the HPLC Market
Founded in 1958 and headquartered in Massachusetts, U.S., Waters Corporation is a specialty measurement company that designs, manufactures, sells, and provides services for high-performance liquid chromatography (HPLC), ultra-performance liquid chromatography (UPLC) and mass spectrometry (MS) technology systems and support products, including chromatography columns, other consumable products, and comprehensive post-warranty service plans. The company also develops and supplies advanced software-based products that interface with its instruments.
Waters Corporation operates through two business segments, namely, Waters and TA. The Waters segment operates in the HPLC market and is engaged in designing, manufacturing, selling, and servicing LC and MS instruments. The TA segment designs, manufactures, sells, and services thermal analysis, rheometry, and calorimetry instruments.
Shimadzu Corporation (Japan)
Founded in 1875 and headquartered in Kyoto, Japan, Shimadzu Corporation offers solutions for human health, safety and security of society, and industrial development. The company operates through four business segments, namely, Analytical and Measuring Instruments Business, Medical Systems Business, Industrial Machinery Business, and Aircraft Equipment Business.
The Analytical and Measuring Instruments business segment operates in the HPLC market and provides a range of liquid chromatography systems, from HPLC to UHPLC, preparative systems, and consumables. The company has 13 R&D facilities and 13 manufacturing facilities globally and a direct geographical presence through its offices in North America, Latin America, Europe, Russia, Middle East & Africa, Asia and Oceania, China, and East Asia. The company operates through a global network and has offices in Brazil, Canada, Chile, China, Egypt, France, Germany, India, Italy, Japan, Mexico, Spain, Switzerland, the U.S., and Turkey.
Thermo Fisher Scientific Inc. (U.S.)
Founded in 2006 and headquartered in Massachusetts, U.S., Thermo Fisher Scientific Inc. is a biotechnology company primarily engaged in life sciences research, improving patient diagnostics, and increasing laboratory productivity.
Thermo Fisher Scientific has four reportable business segments: Life Science Solutions, Analytical Instruments, Specialty Diagnostics, and Laboratory Products and BioPharma Services. The Analytical Instruments segment operates in the HPLC market. This segment is further segmented into three primary businesses, Chromatography and Mass Spectrometry (which offers HPLC products), Chemical Analysis, and Materials and Structural Analysis.
Thermo Fisher serves customers in pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research & academic institutions, government firms, and environmental, industrial quality, and process control settings. Furthermore, it has operations and a presence in approximately 50 countries outside the U.S. and major manufacturing and distribution facilities worldwide, including the U.S., Australia, Canada, China, Denmark, Finland, France, Germany, Japan, Singapore, Sweden, and the U.K.
Agilent Technologies, Inc. (U.S.)
Founded in 1999 and headquartered in California, U.S., Agilent Technologies, Inc. provides application-focused solutions to the life sciences, diagnostics, and applied chemical markets. The company operates through three business segments: Life Sciences and Applied Markets, Diagnostics and Genomics, and Agilent CrossLab.
The Life Sciences and Applied Markets segment offers HPLC products and services. Some of the key product categories of this segment are liquid chromatography (LC) systems and components, liquid chromatography-mass spectrometry (LC-MS) systems, gas chromatography (GC) systems, and flow cytometers. These products have applications in Liquid Chromatography, Gas Chromatography, Mass Spectrometry, Spectroscopy, Software & Informatics, Cell Analysis, Vacuum Technology, Laboratory Automation and Robotics, Chemistries and Supplies, and Remarketed Instruments. Furthermore, this segment has manufacturing and R&D facilities in Australia, China, Germany, Italy, Japan, Malaysia, Netherlands, Singapore, the U.K., and the U.S.
Founded in 1969 and headquartered in Washington, D.C., U.S., Danaher Corporation is a science and technology company. It comprises more than 20 operating companies with positions in life sciences, diagnostics, environmental and applied sectors, organized into three segments: Life Sciences, Diagnostics, and Environmental and Applied Solutions.
The company’s Biotechnology business segment, which was earlier a part of the Life Sciences business segment, offers HPLC products. This segment is further divided into businesses such as Bioprocess, Filtration, Flow Cytometry, Mass Spectrometry, Microscopy, Genomics Consumables, and Gene and Cell Therapy, out of which chromatography products are a part of the Bioprocess business sub-segment, along with cell culture media development services, process liquids, buffers, and cell lines. The Biotechnology business segment includes products from Pall Life Sciences and Cytiva, which were acquired in 2015 and 2020.
Meticulous Research in its latest publication on High-performance Liquid Chromatography (HPLC) Market has predicted the growth of 5.2% during the forecast year 2023-2030
PerkinElmer, Inc. (U.S.)
Founded in 1937 and headquartered in Massachusetts, U.S., PerkinElmer provides products, services, and solutions for diagnostics, life sciences, and applied markets. The company operates through two business segments: Discovery & Analytical Solutions and Diagnostics.
The Discovery & Analytical Solutions segment offers HPLC products. This segment has an extensive portfolio of products and technologies to help researchers in the life science, food, and environmental departments to better understand diseases and develop treatments. The company’s products also help food manufacturers verify product quality and detect and manage contaminants that pollute the environment.
This segment serves the life sciences and applied markets. The company’s key customers include pharmaceutical and biotechnology companies, laboratories, academic and research institutions, public health authorities, private healthcare organizations, doctors, and government agencies.
The company has subsidiaries in Delaware (U.S.), Georgia, Texas, Australia, Austria, Belgium, Brazil, China, Denmark, France, Germany, Hongkong, Italy, India, Japan, Mexico, Turkey, United Arab Emirates (UAE), and the U.K., among others.
Founded in 1668 and headquartered in Darmstadt, Germany, Merck KGaA is a healthcare and technology company. The company operates globally through three major business segments: Life Science, Healthcare, and Electronics. The Life Science Business Segment is further sub-segmented into Research Solutions, Process Solutions, and Applied Solutions.
In February 2022, the Life Sciences segment underwent an organizational transformation, which led to the addition of the Science and Lab Solutions, which include the sub-segments Research Solutions and Applied Solutions, previously sub-segments of the Life Science sector. The company operates in the HPLC market through the Science and Lab Solution segment. This transformation was done to strengthen Contract Development and Manufacturing Organization (CDMO) offerings and to accelerate future growth.
The Process Solution sub-segment provides products for pharmaceutical development and manufacturing as before, including filtration devices, chromatography resins, and processing chemicals. The Life Science business segment has 52 manufacturing sites and over 100 distribution centers.
Bio-Rad Laboratories, Inc. (U.S.)
Founded in 1952 and headquartered in California, U.S., Bio-Rad Laboratories, Inc. develops, manufactures, and markets products for life science research and clinical diagnosis. The company’s products and solutions are based on technologies to separate, purify, identify, analyze, and amplify biological materials, such as cells, bacteria, antibodies, proteins, and nucleic acids.
Bio-Rad Laboratories operates through two business segments: Life Science and Clinical Diagnostics. The Life Science segment operates in the HPLC market and has manufacturing and research sites in Singapore and England (U.K.). The company also provides analytical instruments through its others segment.
Bio-Rad Laboratories has direct distribution channels in over 35 countries outside the U.S. through its subsidiaries.
Hitachi, Ltd. (Japan)
Founded in 1910 and headquartered in Tokyo, Japan, Hitachi, Ltd. is a Japanese multinational conglomerate corporation. The company operates through seven business segments: Digital Systems and Services, Green Energy & Mobility, Connective Industries, Automotive Systems Business, Hitachi Construction Machinery, Hitachi Metals, and Others. The Connective Industries segment operates in the HPLC market through its Advanced Technology Group sub-segment. Apart from HPLC, the other products offered by this segment are clinical chemistry and immunochemistry analyzers, automated cell culture equipment, particle therapy systems, and electron microscopes.
Some of the subsidiaries of the company are Hitachi Solutions Ltd. (Japan), Hitachi Hi-Tech Corporation (Japan), and Hitachi America Capital Ltd. (U.S.).
Founded in 1935 and headquartered in Tokyo, Japan, Tosoh Corporation is a global chemical and specialty materials company that manufactures and sells basic chemicals, specialty products, and petrochemicals. Its product portfolio includes Advanced materials, Bioscience, Cement, Chlor-alkali, Olefins, Organic chemicals, Polymers, and Polyurethanes. The company operates in the HPLC market through the Specialty segment, offering organic chemicals and advanced materials division.
The company’s petrochemical operations supply ethylene, polymers, and polyethylene. They also provide bioscience systems for monitoring life-threatening diseases and preventing epidemics by identifying pathogenic microbes. In addition, the company also provides products and services for water purification and monitoring the environment to commit to a sustainable future.
Tosoh Bioscience, a division of Tosoh Corporation, supplies chromatographic columns, separation and purification media, and sophisticated clinical diagnostic systems and reagents. The company operates and sells its products in Japan, China, Europe, and North America.
Authoritative Research on the High-performance Liquid Chromatography (HPLC) Market – Global Opportunity Analysis and Industry Forecast (2023-2030)
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