The NGS Library Preparation Market is expected to reach $3.62 billion by 2030 at a CAGR of 14.8% from 2023 to 2030. The growth of this market is mainly driven by the declining costs of sequencing, the increasing prevalence of cancer and genetic disorders, the growing utilization of NGS in disease diagnostics and precision medicine and rising R&D investments and healthcare expenditures. However, the availability of alternative technologies and the low chances of identifying positive actionable mutations for precision medicine restrain the growth of this market. The increasing applications of next-generation sequencing technology and collaborations between vendors to develop automated library preparation protocols are expected to create market growth opportunities. However, regulatory and standardization concerns in diagnostic testing and the limited expertise and sequencing capabilities of small & mid-sized laboratories are major challenges to the market’s growth.
Here are the top 10 companies operating in NGS Library Preparation Market
Illumina, Inc. (U.S.)
Incorporated in 1998 and headquartered in California, U.S., Illumina is a provider of sequencing- and array-based solutions for genomic and genetic analysis. The company operates through two reportable segments, namely, Core Illumina and GRAIL. The Core Illumina segment offers a wide range of library preparation and sequencing kits used to simplify workflows and accelerate analysis.
Illumina provides its products to government laboratories, genomic research centers, academic institutions, hospitals, commercial molecular diagnostics laboratories, and pharmaceutical and consumer genomics companies. The company has manufacturing sites and laboratories in the U.S., Singapore, and the U.K.
Through its distributors, Illumina distributes its products globally in North America, Europe, Latin America, Asia-Pacific, and the Middle East & Africa. Illumina Australia Pty. Ltd. (Australia), Illumina Italy S.r.l. (Italy), Illumina Netherlands B.V. (Netherlands) and Illumina K.K. Japan (Japan) are some subsidiaries of the company operating in the NGS library preparation market.
Thermo Fisher Scientific Inc. (U.S.)
Founded in 1956 and headquartered in Massachusetts, U.S., Thermo Fisher offers products and services in the pharmaceutical, biotechnology, agricultural, clinical, healthcare, government, and academic sectors. The company operates through four segments, namely, Life Sciences Solutions, Analytical Instruments, Specialty Diagnostics, and Laboratory Products and Biopharma Services. The Life Sciences Solutions segment offers NGS library preparation products.
Thermo Fisher has a strong geographic presence across North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa through its subsidiaries, R&D sites, and a strong distribution network. As of December 2021, the company had a headcount of 130,000 employees, of which 67,000 were employed in the Americas, 20,000 in Asia-Pacific, and 42,000 in Europe and the Middle East & Africa.
F. Hoffmann-La Roche Ltd (Switzerland)
Founded in 1896 and headquartered in Basel, Switzerland, Roche is a healthcare company that develops, manufactures, and markets a wide range of healthcare solutions. The company has two reportable business divisions, namely, Pharmaceuticals and Diagnostics. Roche operates in the NGS library preparation market through its Diagnostics division.
The Diagnostics division is engaged in developing a wide range of diagnostic products and solutions such as in vitro diagnostics solutions, molecular diagnostics, clinical chemistry & immunoassays, point of care testing, tissue diagnostics, patient self-testing, next-generation sequencing, laboratory automation and IT, and decision support solutions.
Roche has a geographic presence across the U.S., Germany, Switzerland, Japan, China, India, New Zealand, Australia, Latin America, and Africa. Furthermore, the company has 23 manufacturing sites and 29 research and development sites worldwide. Some of its subsidiaries are Genentech (U.S.), Roche Diagnostics (U.S.), Roche Diagnostics GmbH (Germany), Roche Diagnostics (Shanghai) Ltd. (China), Roche Diagnostics (Suzhou) Limited (China), and Roche Diagnostics K.K (Japan).
Agilent Technologies, Inc. (U.S.)
Founded in 1999 and headquartered in California, U.S., Agilent Technologies provides application-focused solutions to the life sciences, diagnostics, and applied chemical markets. The company operates through three business segments: Life Sciences and Applied Markets; Agilent CrossLab; and Diagnostics and Genomics. The Diagnostics and Genomics segment offers products for the NGS library preparation market.
With its subsidiaries and a strong distribution network, Agilent has a presence across North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa and has customers in over 110 countries. The company has research & development and manufacturing sites in California, Colorado, Delaware, Massachusetts, Texas, Vermont, Washington, Australia, China, Denmark, Germany, Italy, Japan, Malaysia, Singapore, and the U.K.
Some of the company’s subsidiaries are Agilent Technologies LLC (Russia), Agilent Technologies Taiwan Ltd. (Taiwan), Agilent Technologies Canada Inc. (Canada), Agilent Technologies UK Limited (U.K.), and Agilent Technologies France SAS (France).
QIAGEN N.V. (Germany)
Founded in 1984 and headquartered in Venlo, Netherlands, QIAGEN is one of the leading providers of sample and assay technologies for molecular diagnostics, applied testing, and academia and pharmaceutical research. The company offers its products through only one reportable segment and provides them in two major markets, Molecular Diagnostics and Life Sciences.
QIAGEN’s product offerings comprise products such as diagnostics solutions, PCR products, genomic or NGS products, consumables and instruments for sample technologies, among others. The company offers more than 500 core products consisting of instruments, kits, and bioinformatics, in addition to a wide range of NGS services like RNA sequencing, DNA sequencing, whole genome amplification, and RNA isolation services, among others.
With facilities in countries like the U.S., China, Germany, Poland, the Philippines, Denmark, Romania, Spain, and the U.K., QIAGEN markets products in more than 130 countries across the globe. The company sells its products through distributors and subsidiaries and directly to its customers. In regions like the Americas, Europe, Asia, and Australia, the sales functions take place mainly through the company’s subsidiaries. Some of its subsidiaries are QIAGEN AB (Sweden), QIAGEN AG (Sweden), and QIAGEN Hamburg GmbH (Germany). As of 2020, QIAGEN had invested about USD 4 million in R&D activities.
“Meticulous Research in its latest publication on NGS Library Preparation Market has predicted the growth of 14.8% during the forecast year 2023-2030”
Merck KGaA (Germany)
Founded in 1668 and headquartered in Darmstadt, Germany, Merck is a German healthcare and technology company that operates globally through its three major business segments, namely, Life Science, Healthcare, and Electronics. The Life Science business segment is further sub-segmented into Research Solutions, Process Solutions, and Applied Solutions. The Research Solutions sub-segment offers NGS library preparation market products for various end users, such as academic institutions, government labs, research hospitals, pharmaceutical companies, R&D, and biotech organizations. In 2021, 90 production sites of the company were covered under the ISO 14001 certification.
Merck has a wide geographic presence in over 150 countries globally. As of December 2021, the company had 60,348 employees across Europe, North America, Asia-Pacific, Latin America, and the Middle East & Africa. The Life Science business segment has 52 manufacturing sites and more than 100 distribution centers. Some of the company’s subsidiaries are Merck Life Science BV (Belgium), Merck Millipore Ltd. (Ireland), Merck Life Science S.r.l. (Italy), Sigma-Aldrich Canada Co. (Canada), Sigma-Aldrich Corporation (U.S.), and Merck Life Science Ltd. (China).
PerkinElmer, Inc. (U.S.)
Founded in 1937 and headquartered in Massachusetts, U.S., PerkinElmer is a multinational company that offers products, solutions, and services for the life sciences, diagnostics, and applied markets. PerkinElmer operates through two reportable business segments: Discovery & Analytical Solutions and Diagnostics. The company offers products for the NGS library preparation market through its Diagnostics business segment.
The manufacturing and R&D facilities of PerkinElmer are located in various countries, including the U.S., China, Japan, and Germany. The company has a strong network of sales and marketing channels. As of January 2021, the company had a headcount of 5,500 sales and service personnel in over 38 countries and marketed its products and services in over 190 countries.
PerkinElmer sells products and services predominantly through its distributors. Some of the company’s subsidiaries are PerkinElmer Genetics, Inc. (U.S.), PerkinElmer Pty. Ltd. (Australia), PerkinElmer do Brasil Ltda. (Brazil), PerkinElmer Instruments (Shanghai) Co. Ltd. (China), PerkinElmer SAS (France), PerkinElmer Technologies GmbH & Co. KG (Germany), PerkinElmer Srl (Italy), PerkinElmer (India) Pvt Ltd. (India), and PerkinElmer Sverige AB (Sweden).
Danaher Corporation (U.S.)
Founded in 1984 and headquartered in Washington D.C., U.S., Danaher Corporation is primarily involved in designing, manufacturing, and marketing medical, professional, industrial, and commercial products and services for various end users. The company operates through three reportable business segments, namely, Life Sciences, Diagnostics, and Environmental & Applied Solutions. In March 2018, Danaher Corporation acquired Integrated DNA Technologies, Inc. (U.S.) to expand its presence in genomics research.
Danaher Corporation offers products in the NGS library preparation market through its Life Sciences segment through its subsidiaries. The company has research and development, manufacturing, sales, distribution, service, and administrative facilities in more than 60 countries across the globe. Furthermore, it has a geographical presence in the U.S., China, Germany, Japan, and several other countries. Danaher Corporation sells its products through direct sales personnel and independent distributors.
Danaher Corporation offers products in the NGS library preparation market through its subsidiaries, such as Beckman Coulter, Inc. (U.S.) and Integrated DNA Technologies, Inc. (U.S.). Some other subsidiaries are Beckman Coulter Biomedical Ltd. (Ireland), Beckman Coulter Commercial Enterprise Co., Ltd. (China), Beckman Coulter France S.A.S. (France), Beckman Coulter Australia Pty. Ltd. (Australia), Beckman Coulter Korea Ltd. (South Korea), and Beckman Coulter LLC (Russia).
Tecan Group Ltd. (Switzerland)
Founded in 1980 and headquartered in Männedorf, Switzerland, Tecan Group is engaged in developing, producing, and marketing automated laboratory instruments and solutions for applications in biopharmaceuticals, forensics, and clinical diagnostics. The company provides its products to pharmaceutical and biotechnology companies, university research departments, and diagnostic laboratories.
Tecan Group operates through two reportable business segments, namely, Life Sciences Business and Partnering Business. The company provides products in the NGS library preparation through its Life Sciences Business segment.
The Life Sciences Business has a wide geographic presence and distributes products through its market organizations and distributors in more than 70 countries across the globe. Some of the company’s subsidiaries are Tecan Genomics, Inc. (U.S.), Tecan France S.A.S. (France), Tecan Italia S.r.l. (Italy), Tecan UK Ltd. (U.K.), Tecan Japan Co., Ltd. (Japan), and Tecan Australia Pty Ltd (Australia).
Pacific Biosciences of California, Inc. (U.S.)
Incorporated in 2004 and headquartered in California, U.S., Pacific Biosciences of California is a life science technology company that designs, develops, and manufactures advancing sequencing solutions that help researchers and scientists solve genetically complex problems. The company focuses on two core technologies: HiFi long-read sequencing technology and short read Sequencing by Binding (SBB) technology. Pacific Biosciences’ products address solutions to various applications, including plant and animal sciences, human germline sequencing, oncology, infectious disease and microbiology, and other emerging applications.
Pacific Biosciences operates in one reportable business segment and provides its products to various end users such as governmental and academic research institutions, service laboratories and commercial testing, genome centers, hospitals and clinical research institutions, public health labs, contract research organizations (CROs), agricultural and pharmaceutical companies.
The company has a direct presence across the U.K. in Europe, China, Japan, South Korea, Singapore, Asia-Pacific, and the Middle East & Africa.
Popular Mentions: Diagenode S.A. (Belgium) (Subsidiary of Hologic, Inc. (U.S.)), New England Biolabs, Inc. (U.S.), Zymo Research Corporation (U.S.), Norgen Biotek Corp. (Canada).
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